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1

Cholestasis-induced pruritus treated with ultraviolet B phototherapy: An observational case series study

Sofie Decock, Rik Roelandts, Werner Van Steenbergen, Wim Laleman, David Cassiman, Chris Verslype, Johan Fevery, Jos Van Pelt, Frederik Nevens

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 569 KB

english, 2012

2

Endogenizing know-how flows through the nature of R&D investments

Bruno Cassiman, David Pérez-Castrillo, Reinhilde Veugelers

Journal:

International Journal of Industrial Organization

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

3

Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

David Cassiman, Louis Libbrecht, Valeer Desmet, Carl Denef, Tania Roskams

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 912 KB

english, 2002

4

A novel mutation causing mild, atypical fumarylacetoacetase deficiency (Tyrosinemia type I): a case report

David Cassiman, Renate Zeevaert, Elisabeth Holme, Eli-Anne Kvittingen, Jaak Jaeken

Journal:

Orphanet Journal of Rare Diseases

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

5

Clinical evidence for orphan medicinal products-a cause for concern?

Picavet, Eline, Cassiman, David, Hollak, Carla E, Maertens, Johan A, Simoens, Steven

Journal:

Orphanet Journal of Rare Diseases

Year:

2013

Language:

english

File:

PDF, 204 KB

english, 2013

6

Development and validation of COMPASS: clinical evidence of orphan medicinal products – an assessment tool

Picavet, Eline, Cassiman, David, Aertgeerts, Bert, Simoens, Steven

Journal:

Orphanet Journal of Rare Diseases

Year:

2013

Language:

english

File:

PDF, 171 KB

english, 2013

7

Shining a light in the black box of orphan drug pricing

Picavet, Eline, Morel, Thomas, Cassiman, David, Simoens, Steven

Journal:

Orphanet Journal of Rare Diseases

Year:

2014

Language:

english

File:

PDF, 226 KB

english, 2014

8

Reimbursement of orphan drugs in Belgium: what (else) matters?

Picavet, Eline, Cassiman, David, Simoens, Steven

Journal:

Orphanet Journal of Rare Diseases

Year:

2014

Language:

english

File:

PDF, 266 KB

english, 2014

9

Neurocognitive outcome in tyrosinemia type 1 patients compared to healthy controls

van Ginkel, Willem G., Jahja, Rianne, Huijbregts, Stephan C. J., Daly, Anne, MacDonald, Anita, De Laet, Corinne, Cassiman, David, Eyskens, François, Körver-Keularts, Irene M. L. W., Goyens, Philippe J

Journal:

Orphanet Journal of Rare Diseases

Year:

2016

Language:

english

File:

PDF, 746 KB

english, 2016

10

Off-label use of orphan medicinal products: a Belgian qualitative study

Dooms, Marc, Cassiman, David, Simoens, Steven

Journal:

Orphanet Journal of Rare Diseases

Year:

2016

Language:

english

File:

PDF, 435 KB

english, 2016

11

Unusual yellow scaly colonic mucosal appearance: Tangier disease

Struyve, Mathieu, Ferrante, Marc, Van Overbeke, Lode, Meersseman, Wouter, Cassiman, David

Journal:

Gastrointestinal Endoscopy

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

12

Response by Kusters et al to Letter Regarding Article, “Effect of Rosuvastatin on Carotid Intima-Media Thickness in Children With Heterozygous Familial Hypercholesterolemia: The CHARON Study (Hypercholesterolemia in Children and Adolescents Taking Rosuvastatin Open Label)”

Kusters, D. Meeike, Braamskamp, Marjet J.A.M., Langslet, Gisle, McCrindle, Brian W., Cassiman, David, Francis, Gordon A., Gagne, Claude, Gaudet, Daniel, Morrison, Katherine M., Wiegman, Albert, Turner

Journal:

Year:

2018

Language:

english

File:

PDF, 114 KB

english, 2018

13

Liver transplantation for very severe hepatopulmonary syndrome due to vitamin A-induced chronic liver disease in a patient with Shwachman-Diamond syndrome

Bucciol, Giorgia, Cassiman, David, Roskams, Tania, Renard, Marleen, Hoffman, Ilse, Witters, Peter, Schrijvers, Rik, Schaballie, Heidi, Bosch, Barbara, Putti, Maria Caterina, Gheysens, Olivier, Knops,

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 696 KB

english, 2018

14

Emotional and behavioral problems, quality of life and metabolic control in NTBC-treated Tyrosinemia type 1 patients

van Vliet, Kimber, van Ginkel, Willem G., Jahja, Rianne, Daly, Anne, MacDonald, Anita, De Laet, Corinne, Vara, Roshni, Rahman, Yusof, Cassiman, David, Eyskens, Francois, Timmer, Corrie, Mumford, Nicky

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

Language:

english

File:

PDF, 677 KB

english, 2019

15

Emotional and behavioral problems, quality of life and metabolic control in NTBC-treated Tyrosinemia type 1 patients

van Vliet, Kimber, van Ginkel, Willem G., Jahja, Rianne, Daly, Anne, MacDonald, Anita, De Laet, Corinne, Vara, Roshni, Rahman, Yusof, Cassiman, David, Eyskens, Francois, Timmer, Corrie, Mumford, Nicky

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

File:

PDF, 677 KB

2019

16

Two cases of non-alcoholic fatty liver disease caused by biallelic ABHD5 mutations

Adant, Isabelle, Declercq, Mathias, Bird, Matthew, Bauters, Marijke, Boeckx, Nancy, Devriendt, Koen, Cassiman, David, Witters, Peter

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 588 KB

2020

17

Neuroregulation of the neuroendocrine compartment of the liver

Tania Roskams, David Cassiman, Rita De Vos, Louis Libbrecht

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2004

Language:

english

File:

PDF, 667 KB

english, 2004

18

The correlation between portal myofibroblasts and development of intrahepatic bile ducts and arterial branches in human liver

Louis Libbrecht, David Cassiman, Valeer Desmet, Tania Roskams

Journal:

Liver International

Year:

2002

Language:

english

File:

PDF, 1.22 MB

english, 2002

19

The TNFα receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis

Frauke Stanke, Tim Becker, Harry Cuppens, Vinod Kumar, Jean-Jacques Cassiman, Silke Jansen, Dragica Radojkovic, Benny Siebert, Jennifer Yarden, David W. Ussery, Thomas F. Wienker, Burkhard Tümmler

Journal:

Year:

2006

Language:

english

File:

PDF, 469 KB

english, 2006

20

Lysosomal lipid vacuoles in macrophages located in the colon

Wouter Meersseman, Steven Vanderschueren, Rita De Vos, David Cassiman

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 137 KB

english, 2010

21

Hepatitis B virus replication causes oxidative stress in HepAD38 liver cells

Tamara Severi, Chunxiao Ying, Joris Robert Vermeesch, David Cassiman, Lieselotte Cnops, Chris Verslype, Johan Fevery, Lutgarde Arckens, Johan Neyts, Jos F. van Pelt

Journal:

Molecular and Cellular Biochemistry

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

22

Community genetics. Its definition 2010

Leo P. ten Kate, Lihadh Al-Gazali, Sonia Anand, Alan Bittles, Jean-Jacques Cassiman, Arnold Christianson, Martina C. Cornel, Hanan Hamamy, Helena Kääriäinen, Ulf Kristoffersson, David Marais, Victor B

Journal:

Journal of Community Genetics

Year:

2010

Language:

english

File:

PDF, 89 KB

english, 2010

23

Orlistat treatment is safe in overweight and obese liver transplant recipients: a prospective, open label trial

David Cassiman, Mieke Roelants, Gerda Vandenplas, Schalk W. Van der Merwe, Ann Mertens, Louis Libbrecht, Chris Verslype, Johan Fevery, Raymond Aerts, Jacques Pirenne, Erik Muls, Frederik Nevens

Journal:

Transplant International

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

24

Cholestatic liver disease in long-term infantile nephropathic cystinosis

Tom Cornelis, Kathleen Claes, Pieter Gillard, Els Nijs, Tania Roskams, Rita Lombaerts, Frederik Nevens, David Cassiman

Journal:

Journal of Gastroenterology and Hepatology

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

25

Human hepatic progenitor cells express vasoactive intestinal peptide receptor type 2 and receive nerve endings

David Cassiman, Nicoletta Sinelli, Ilse Bockx, Sara Vander Borght, Bryon Petersen, Rita De Vos, Jos Van Pelt, Frederik Nevens, Louis Libbrecht, Tania Roskams

Journal:

Liver International

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

26

Carbon monoxide produced by intrasinusoidally located haem-oxygenase-1 regulates the vascular tone in cirrhotic rat liver

Lien Van Landeghem, Wim Laleman, Ingrid Vander Elst, Marcel Zeegers, Jos Van Pelt, David Cassiman, Frederik Nevens

Journal:

Liver International

Year:

2009

Language:

english

File:

PDF, 974 KB

english, 2009

27

The hepatic vagus nerve stimulates hepatic stellate cell proliferation in rat acute hepatitis via muscarinic receptor type 2

Ilse Bockx, Ingrid Vander Elst, Tania Roskams, David Cassiman

Journal:

Liver International

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

28

Distinct haematological disorder with deletion of long arm of No. 5 chromosome

VAN DEN BERGHE, HERMAN, CASSIMAN, JEAN-JACQUES, DAVID, GUIDO, FRYNS, JEAN-PIERRE, MICHAUX, JEAN-LOUIS, SOKAL, GERARD

Journal:

Year:

1974

File:

PDF, 221 KB

1974

29

Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors

David Cassiman, Carl Denef, Valeer J. Desmet, Tania Roskams

Journal:

Year:

2001

Language:

english

File:

PDF, 1.20 MB

english, 2001

30

Orphan Drugs for Rare Diseases: Grounds for Special Status

Eline Picavet, Marc Dooms, David Cassiman, Steven Simoens

Journal:

Drug Development Research

Year:

2012

Language:

english

File:

PDF, 76 KB

english, 2012

31

Mapping of human fibronectin receptorβsubunit gene to chromosome 10

Yong Zhang, Marc Saison, Marijke Spaepen, Bart De Strooper, Fred Van Leuven, Guido David, Herman Van den Berghe, Jean-Jacques Cassiman

Journal:

Somatic Cell and Molecular Genetics

Year:

1988

Language:

english

File:

PDF, 546 KB

english, 1988

32

Differences in agglutinability of adult and fetal human fibroblasts using phytohemagglutinin

Jean-Jaques Cassiman, Guido David, Bernadette Van Der Schueren, Herman Van Den Berghe

Journal:

Cell Differentiation

Year:

1977

Language:

english

File:

PDF, 1.10 MB

english, 1977

33

HBx or HCV core gene expression in HepG2 human liver cells results in a survival benefit against oxidative stress with possible implications for HCC development

Tamara Severi, Sara Vander Borght, Louis Libbrecht, Lucas VanAelst, Frederik Nevens, Tania Roskams, David Cassiman, Johan Fevery, Chris Verslype, Jos F. van Pelt

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

34

Left ventricular assist device as bridge to liver transplantation in a patient with propionic acidemia and cardiogenic shock

Koen Ameloot, Dirk Vlasselaers, Matthias Dupont, Wouter Meersseman, Lars Desmet, Johan Vanhaecke, Nina Vermeer, Bart Meyns, Jacques Pirenne, David Cassiman, Corinne De Laet, Philippe Goyens, Sophie G.

Journal:

The Journal of Pediatrics

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

35

Histology obtained by needle biopsy gives additional information on the prognosis of hepatocellular carcinoma

Hannah van Malenstein, Mina Komuta, Chris Verslype, Vincent Vandecaveye, Ben Van Calster, Baki Topal, Wim Laleman, David Cassiman, Werner Van Steenbergen, Raymond Aerts, Dirk Vanbeckevoort, Didier Bie

Journal:

Hepatology Research

Year:

2012

Language:

english

File:

PDF, 600 KB

english, 2012

36

Heparan sulfate proteoglycans of human lung fibroblasts : Occurrence of distinct membrane, matrix and secreted forms

Veerle LORIES, Guido DAVID, Jean-Jacques CASSIMAN, Herman VAN DEN BERGHE

Journal:

Year:

1986

Language:

english

File:

PDF, 1002 KB

english, 1986

37

Post-translational modification of the β-subunit of the human fibronectin receptor

Martine Jaspers, Bart de Strooper, Marijke Spaepen, Fred van Leuven, Guido David, Herman van den Berghe, Jean-Jacques Cassiman

Journal:

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

38

Hepatic vagotomy inhibits proliferation of hepatic stellate cells in rats with acute hepatitis

Ilse Bockx, Nicoletta Sinelli, Ingrid Vander Elst, Louis Libbrecht, Tania Roskams, David Cassiman

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

39

Disturbed glucose homeostasis in vagotomized rats with taa-hepatitis: An explanation for post liver transplant diabetes

Ilse Bockx, Marcel Zeegers, Ingrid Vander Elst, Jos van Pelt, Frederik Nevens, Jan Tack, David Cassiman

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

40

Hepatic stellate cells do not derive from the neural crest

David Cassiman, Amanda Barlow, Sara Vander Borght, Louis Libbrecht, Vassilis Pachnis

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 374 KB

english, 2006

41

An adult male patient with multiple adenomas and a hepatocellular carcinoma: Mild Glycogen Storage Disease type Ia

David Cassiman, Louis Libbrecht, Chris Verslype, Wouter Meersseman, Roberto Troisi, Jessica Zucman-Rossi, Hans Van Vlierberghe

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 690 KB

english, 2010

42

The Vagal Nerve Stimulates Activation of the Hepatic Progenitor Cell Compartment via Muscarinic Acetylcholine Receptor Type 3

David Cassiman, Louis Libbrecht, Nicoletta Sinelli, Valeer Desmet, Carl Denef, Tania Roskams

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 2.15 MB

english, 2002

43

Synaptophysin: A Novel Marker for Human and Rat Hepatic Stellate Cells

David Cassiman, Jos van Pelt, Rita De Vos, Fons Van Lommel, Valeer Desmet, Sing-Hiem Yap, Tania Roskams

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 2.99 MB

english, 1999

44

PAS-positive macrophages—not always infection

Wouter Meersseman, Patrick Verschueren, Thomas Tousseyn, Rita De Vos, David Cassiman

Journal:

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

45

Up-regulation of breast cancer resistance protein expression in hepatoblastoma following chemotherapy: A study in patients and in vitro

Sara Vander Borght, Jos Van Pelt, Hannah Van Malenstein, David Cassiman, Marleen Renard, Chris Verslype, Louis Libbrecht, Tania A. Roskams

Journal:

Hepatology Research

Year:

2008

Language:

english

File:

PDF, 483 KB

english, 2008

46

Expression of neural cell adhesion molecule in human liver development and in congenital and acquired liver diseases

Louis Libbrecht, David Cassiman, Valeer Desmet, Tania Roskams

Journal:

Histochemistry and Cell Biology

Year:

2001

Language:

english

File:

PDF, 412 KB

english, 2001

47

Beauty is in the eye of the beholder: emerging concepts and pitfalls in hepatic stellate cell research

David Cassiman, Tania Roskams

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 641 KB

english, 2002

48

The vagal nerve stimulates growth of the human and rat hepatic progenitor cell compartment, via muscarinic acetylcholine receptor 3

David Cassiman, Louis Libbrecht, Nicoletta Sinelli, Valeer Desmet, Carl Denef, Tania Roskams

Journal:

Journal of Hepatology

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

49

Growth properties and in vitro life span of Alzheimer disease and Down syndrome fibroblasts. A blind study

Geert Carmeliet, Rik Hauma, Rene Dom, Guido David, Jean-Pierre Fryns, Herman van den Berghe, Jean-Jacques Cassiman

Journal:

Mechanisms of Ageing and Development

Year:

1990

Language:

english

File:

PDF, 682 KB

english, 1990

50

Evaluating and improving orphan drug regulations in Europe: A Delphi policy study

Picavet, Eline, Cassiman, David, Simoens, Steven

Journal:

Year:

2012

Language:

english

File:

PDF, 257 KB

english, 2012